CRYONANO
THINK SCIENCE
Cryogenic NanoStage
CryoNano Cryogenic NanoStage is a high-precision, liquid-nitrogen–cooled microscopy stage designed for cryo-fluorescence imaging, cryo-correlative light and electron microscopy, and cryo-super-resolution workflows
Engineered to maintain samples in a fully vitrified state, the Cryogenic NanoStage enables safe handling, transfer, and imaging of cryo-samples while preventing contamination. The system supports coordinate-mapped imaging, allowing users to reliably relocate the same region of interest across multiple complementary modalities such as TEM, FIB-SEM, SEM, and X-ray microscopy.
Sample Integrity & Handling System
Engineered to preserve vitrification and eliminate contamination throughout cryo-imaging workflows.
Cryogenic Stability Without Compromise
The CRYONANO Cryogenic NanoStage maintains vitrified samples through continuous liquid nitrogen cooling, keeping temperatures below –195°C.
This prevents devitrification, ice crystal formation, and atmospheric contamination during observation and handling.
A sealed, frost-controlled environment enables extended cryo-imaging sessions while preserving structural integrity.
Intelligent Sample Handling
Controlled Cryogenic
Transfer
A dedicated cryogenic transfer container enables safe movement from plunge freezing or high-pressure freezing systems directly into the NanoStage ; without exposure to ambient moisture.
Samples mounted on EM grids or cryo-compatible carriers transition seamlessly between optical and electron microscopy.
Integrated Cassette System
-
Self-aligning magnetic sample cassette
-
Supports up to three EM grids per cassette
-
Secure, contamination-free loading and storage
-
Broad carrier compatibility
Supported Sample Formats
Compatible With:
-
Standard EM grids
-
Planchettes
-
Bessy grids
-
Silicon nitride frames
-
Custom sample holders
Features
The CRYONANO Cryogenic NanoStage is engineered for ease of use, operational reliability, and streamlined workflow efficiency. It offers rapid startup with minimal preparation time, enabling researchers to begin experiments quickly without complex setup procedures.
A cordless, heated, frost-free viewing lid ensures clear visibility during operation, while an integrated LED condenser provides brightfield transmitted illumination for precise sample observation. Real-time temperature monitoring through embedded sensors maintains consistent cryogenic conditions throughout imaging. The interchangeable cryo-bridge architecture allows adaptation to custom experimental requirements, and an optional objective lens heater further enhances thermal stability, minimizing drift during high-resolution imaging.
Benefits
Guaranteed Vitrification Integrity: Maintains stable temperatures below –195 °C to eliminate devitrification and preserve ultrastructural fidelity.
Zero Frost. Zero Moisture. Zero Compromise.: A sealed cryogenic chamber prevents atmospheric contamination during imaging and transfer.
Nanoscale Positional Accuracy: Motorized XY mapping enables precise grid navigation and repeatable targeting for advanced workflows.
Efficient Multi-Sample Workflow: Integrated magnetic cassette supports up to three EM grids for streamlined experimentation.
.png)
Researcher-Friendly Control: Ergonomic joystick and software interface enable smooth operation and reduced training time.
.png)
Platform-Agnostic Integration: Compatible with standard EM grids, autogrids, membrane carriers, and leading microscopy platforms.
.jpg)
Built for Advanced Cryo Workflows: Engineered for Cryo-CLEM, cryo-super-resolution, and quantum-scale material investigations.